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Article

Perfusion parameters derived from MRI for preoperative prediction of IDH mutation and MGMT promoter methylation status in glioblastomas.

Magnetic resonance imaging - 1 Nov 2021

Lu Jun, Li Xiang, Li Hailiang

Abstract excerpt

PURPOSE: To investigate the feasibility for preoperative prediction of IDH mutation and MGMT promoter methylation status in glioblastomas(GBMs) by intravoxel incoherent motion(IVIM) and dynamic susceptibility contrast(DSC). METHODS: Preoperative IVIM and DSC images of 71 patients(IDH mutation:45, IDH wildtype: 26; MGMT methylation: 31, MGMT unmethylation:40) with glioblastomas were analyzed retrospectively....

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PMID: 34506909
DOI: 10.1016/j.mri.2021.09.005

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