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Article

Inferring causal relationships between phenotypes using summary statistics from genome-wide association studies.

Human genetics - 1 Mar 2018

Meng Xiang-He, Shen Hui, Chen Xiang-Ding, Xiao Hong-Mei, Deng Hong-Wen

Abstract excerpt

Genome-wide association studies (GWAS) have successfully identified numerous genetic variants associated with diverse complex phenotypes and diseases, and provided tremendous opportunities for further analyses using summary association statistics. Recently, Pickrell et al. developed a robust method for causal inference using independent putative causal SNPs. However, this method may fail to infer the causal...

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Identifiers

PMID: 29460149
DOI: 10.1007/s00439-018-1876-1
PMCID: PMC6343668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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