Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence

Abstract excerpt

Cellular senescence response is (i) activated by numerous stresses, (ii) is characterized by a stable proliferation arrest, and (iii) by a set of specific features. Timely regulated senescence is thought to be beneficial, whereas chronic senescence such as during normal or premature aging is deleterious as it favors most, if not all, age-related diseases. In this study, using in-house or publicly available...

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• Share to Advanced biosensing and bioanalysis techniques
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