Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology.

doi:10.1161/CIRCGEN.117.001813

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Article

Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology.

Circulation. Genomic and precision medicine - 1 Feb 2018

Lovering Ruth C, Roncaglia Paola, Howe Douglas G, Laulederkind Stanley J F, Khodiyar Varsha K, Berardini Tanya Z, Tweedie Susan, Foulger Rebecca E, Osumi-Sutherland David, Campbell Nancy H, Huntley Rachael P, Talmud Philippa J, Blake Judith A, Breckenridge Ross, Riley Paul R, Lambiase Pier D, Elliott Perry M, Clapp Lucie, Tinker Andrew, Hill David P

Abstract excerpt

BACKGROUND: A systems biology approach to cardiac physiology requires a comprehensive representation of how coordinated processes operate in the heart, as well as the ability to interpret relevant transcriptomic and proteomic experiments. The Gene Ontology (GO) Consortium provides structured, controlled vocabularies of biological terms that can be used to summarize and analyze functional knowledge for gene...

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PMID: 29440116
DOI: 10.1161/CIRCGEN.117.001813
PMCID: PMC5821137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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