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Role of autophagy in breast cancer and breast cancer stem cells (Review)

8 Feb 2018

Abstract excerpt

Autophagy is a key catabolic process, in which cytosolic cargo is engulfed by the formation of a double membrane and then degraded through the fusing of autophagosomes with lysosomes. Autophagy is a constitutively active, evolutionarily conserved, catabolic process important for the maintenance of homeostasis in cellular stress responses and cell survival. Although the mechanisms of autophagy have not yet been...

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PMID: 29436618
DOI: 10.3892/ijo.2018.4270

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