Article
Impact of inter-genotypic recombination and probe cross-reactivity on the performance of the Abbott RealTime HCV Genotype II assay for hepatitis C genotyping.
Diagnostic microbiology and infectious disease - 1 May 2018
Sridhar Siddharth, Yip Cyril C Y, Chan Jasper F W, To Kelvin K W, Cheng Vincent C C, Yuen Kwok-Yung
Abstract excerpt
The Abbott RealTime HCV Genotype II assay (Abbott-RT-HCV assay) is a real-time PCR based genotyping method for hepatitis C virus (HCV). This study measured the impact of inter-genotypic recombination and probe cross-reactivity on the performance of the Abbott-RT-HCV assay. 517 samples were genotyped using the Abbott-RT-HCV assay over a one-year period, 34 (6.6%) were identified as HCV genotype 1 without further...
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