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Article

Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis.

EBioMedicine - 1 Mar 2018

Karachaliou Niki, Chaib Imane, Cardona Andres Felipe, Berenguer Jordi, Bracht Jillian Wilhelmina Paulina, Yang Jie, Cai Xueting, Wang Zhigang, Hu Chunping, Drozdowskyj Ana, Servat Carles Codony, Servat Jordi Codony, Ito Masaoki, Attili Ilaria, Aldeguer Erika, Capitan Ana Gimenez, Rodriguez July, Rojas Leonardo, Viteri Santiago, Molina-Vila Miguel Angel, Ou Sai-Hong Ignatius, Okada Morihito, Mok Tony S, Bivona Trever G, Ono Mayumi, Cui Jean, Ramón Y Cajal Santiago, Frias Alex, Cao Peng, Rosell Rafael

Abstract excerpt

Epidermal growth factor receptor (EGFR)-mutation-positive non-smallcell lung cancer (NSCLC) is incurable, despite high rates of response to EGFR tyrosine kinase inhibitors (TKIs). We investigated receptor tyrosine kinases (RTKs), Src family kinases and focal adhesion kinase (FAK) as genetic modifiers of innate resistance in EGFR-mutation-positive NSCLC. We performed gene expression analysis in two cohorts (Cohort...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Axl Receptor Tyrosine Kinase

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Source

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Identifiers

PMID: 29433983
DOI: 10.1016/j.ebiom.2018.02.001
PMCID: PMC5925453

Genes

EGFR
CDCP1
AXL
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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