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Article

Monocyte subsets and their phenotypes during treatment with BCR-ABL1 tyrosine kinase inhibitors for Philadelphia chromosome-positive leukemia.

Hematological oncology - 1 Apr 2018

Konuma Takaaki, Kohara Chisato, Watanabe Eri, Mizukami Motoko, Nagai Etsuko, Tanoue Susumu, Isobe Masamichi, Jimbo Koji, Kato Seiko, Ohno Nobuhiro, Takahashi Satoshi, Tojo Arinobu

Abstract excerpt

BCR-ABL1 tyrosine kinase inhibitors (TKIs) are effective agents in the treatment of Philadelphia chromosome-positive leukemia. However, vascular events have developed in some patients receiving each TKI. The perturbation of circulating monocyte subsets and their expressions of chemokine and scavenger receptors are associated with the development of cardiovascular events. Here, we examined the subsets of...

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Share to Dasatinib
Share to Fusion Proteins, bcr-abl

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Share to Receptors, Chemokine

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Source

Identifiers

PMID: 29431866
DOI: 10.1002/hon.2497

Genes

ABL1
BCR
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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