Negative regulators that mediate ocular immune privilege

Abstract excerpt

The ocular microenvironment has adapted several negative regulators of inflammation to maintain immune privilege and health of the visual axis. Several constitutively produced negative regulators within the eye TGF-β2, α-melanocyte stimulating hormone (α-MSH), Fas ligand (FasL), and PD-L1 standout because of their capacity to influence multiple pathways of inflammation, and that they are part of promoting immune...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Glaucoma and retinal disorders
• Share to Immune Response and Inflammation
• Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms