Article
Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease.
BMC genomics - 9 Feb 2018
Versteeg Bart, Bruisten Sylvia M, Pannekoek Yvonne, Jolley Keith A, Maiden Martin C J, van der Ende Arie, Harrison Odile B
Abstract excerpt
BACKGROUND: Chlamydia trachomatis (Ct) plasmid has been shown to encode genes essential for infection. We evaluated the population structure of Ct using whole-genome sequence data (WGS). In particular, the relationship between the Ct genome, plasmid and disease was investigated. RESULTS: WGS data from 157 Ct isolates deposited in the Chlamydiales pubMLST database ( http://pubMLST.org/chlamydiales/ ) were...
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