Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Optimized angiotensin-converting enzyme activity assay for the accurate diagnosis of sarcoidosis.

Clinical chemistry and laboratory medicine - 27 Jun 2018

Csongrádi Alexandra, Enyedi Attila, Takács István, Végh Tamás, Mányiné Ivetta S, Pólik Zsófia, Altorjay István Tibor, Balla József, Balla György, Édes István, Kappelmayer János, Tóth Attila, Papp Zoltán, Fagyas Miklós

Abstract excerpt

BACKGROUND: Serum angiotensin-converting enzyme (ACE) activity determination can aid the early diagnosis of sarcoidosis. We aimed to optimize a fluorescent kinetic assay for ACE activity by screening the confounding effects of endogenous ACE inhibitors and interfering factors. Genotype-dependent and genotype-independent reference values of ACE activity were established, and their diagnostic accuracies were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Enzyme Assays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ACE gene

Share to Genotype

Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Genetic

Share to Reference Values

Share to Sarcoidosis

Source

Identifiers

PMID: 29425104
DOI: 10.1515/cclm-2017-0837

Genes

ACE
FRK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Optimized angiotensin-converting enzyme activity assay for the accurate diagnosis of sarcoidosis.PMID 29425104Read ↗

Genotyping increases the yield of angiotensin-converting enzyme in sarcoidosis--a systematic review.Semantic proximity Read ↗

Clinical value of ACE genotyping in diagnosis of sarcoidosisSemantic proximity Read ↗

Genotype-corrected reference values for serum angiotensin-converting enzyme.Semantic proximity Read ↗

Development of a high-resolution melting genotyping assay for the angiotensin I converting enzyme insertion/deletion polymorphism and establishment of genotype-specific reference intervals in a Danish population.Semantic proximity Read ↗

[Corrected normal values for serum ACE by genotyping the deletion-/insertion-polymorphism of the ACE gene].Semantic proximity Read ↗

ACE I/D-corrected Z-scores to identify normal and elevated ACE activity in sarcoidosis.Semantic proximity Read ↗

ACE I/D genotype influences longitudinal serum ACE activity in sarcoidosis.Semantic proximity Read ↗

Predictive Potential of ACE phenotyping in Extrapulmonary SarcoidosisSemantic proximity Read ↗

Influence of angiotensin converting enzyme (ACE) genotype on interpretation of diagnostic tests for serum ACE activity.Semantic proximity Read ↗

Association between ACE gene I/D polymorphism and clinical presentation and prognosis of sarcoidosis.Semantic proximity Read ↗

Extreme elevation of serum angiotensin-converting enzyme (ACE) activity: always consider familial ACE hyperactivity.Semantic proximity Read ↗

Angiotensin converting enzyme (ACE) gene polymorphism in sarcoidosis in relation to associated autoimmune diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.