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Article

ACE I/D genotype influences longitudinal serum ACE activity in sarcoidosis.

Gene - 5 Jun 2026

Leffers Henrik Christian Bidstrup, Graudal Niels, Krintel Sophine B, Lindhardsen Jesper, Høy Anne Meldgaard, Baslund Bo

Abstract excerpt

PURPOSE: Serum angiotensin-converting enzyme (sACE) is widely used as a biomarker in sarcoidosis, yet interpretation is complicated by genetic variability. We investigated whether ACE insertion/deletion (I/D) genotype influences longitudinal sACE activity and its relationship to clinical manifestations and treatment response. METHODS: Forty-six patients with confirmed sarcoidosis and available ACE genotype data...

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Identifiers

PMID: 41871628
DOI: 10.1016/j.gene.2026.150115

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ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

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