Article
The prevalence of HLA alleles in a lupus nephritis population.
Transplant immunology - 1 Apr 2018
de Holanda Maria Izabel, Klumb Evandro, Imada Alicia, Lima Livia A, Alcântara Isabela, Gregório Flavia, Christiani Luis Fernando, Martins Clarice Oliveira, Timoner Branca Engel, Motta Juliana, Pozzan Roberto, Pôrto Luis Cristóvão
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is a severe autoimmune disease that involves multiple organ systems. Lupus nephritis (LN) is a complication of SLE and is associated with poor survival and high morbidity. Many genomic studies have been performed worldwide, and several histocompatibility leukocyte antigen (HLA) loci are linked to lupus susceptibility. OBJECTIVE: The present study evaluated the...
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