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Article

Investigating the mechanisms of hyporesponse to antiplatelet approaches.

Clinical cardiology - 1 Mar 2008

Braunwald Eugene, Angiolillo Dominick, Bates Eric, Berger Peter B, Bhatt Deepak, Cannon Christopher P, Furman Mark I, Gurbel Paul, Michelson Alan D, Peterson Eric, Wiviott Stephen

Abstract excerpt

Hyporesponsiveness, or resistance, to antiplatelet therapy may be a major contributor to poorer outcomes among cardiac patients and may be attributed to an array of mechanisms--both modifiable and unmodifiable. Recent evidence has uncovered clinical, cellular, and genetic factors associated with hyporesponsiveness. Patients with severe acute coronary syndromes (ACS), type 2 diabetes, and increased body mass index...

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Source

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Identifiers

PMID: 18481819
DOI: 10.1002/clc.20360
PMCID: PMC6653508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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