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Generation of 2 induced pluripotent stem cell lines derived from patients with Parkinson's disease carrying LRRK2 G2385R variant.

Stem cell research - 1 Apr 2018

Cheng Yu-Che, Huang Ching-Ying, Ho Ming-Ching, Hsu Yu-Hung, Syu Shih-Han, Lu Huai-En, Lin Han-I, Lin Chin-Hsien, Hsieh Patrick C H

Abstract excerpt

Leucine rich repeat kinase (LRRK2) is the most prevalent genetic cause for Parkinson's disease. LRRK2 p.G2385R is an Asian specific genetic risk factor for sporadic Parkinson's disease. We generated two induced pluripotent stem cells (iPSCs), IBMS-iPSC-018-09 and IBMS-iPSC-020-01, from the peripheral blood mononuclear cells of two patients carrying LRRK2 p.G2385R variant by using the Sendai-virus delivery system....

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Identifiers

PMID: 29414410
DOI: 10.1016/j.scr.2018.01.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Generation of 2 induced pluripotent stem cell lines derived from patients with Parkinson's disease carrying LRRK2 G2385R variant.PMID 29414410Read ↗

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