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Reprogramming of a human induced pluripotent stem cell (iPSC) line from a Parkinson's disease patient with a R1628P variant in the LRRK2 gene.

Stem cell research - 1 Jan 2017

Ma Dongrui, Zhou Wei, Ng Ebonne Yulin, Zeng Li, Zhao Yi, Tan Eng King

Abstract excerpt

Peripheral blood mononuclear cells (PBMCs) were collected from a clinically diagnosed 59-year old male Parkinson's disease (PD) patient with R1628P variant in the LRRK2 gene. The PMBCs were reprogrammed with the human OSKM transcription factors using the Sendai-virus reprogramming system. The transgene-free iPSC showed pluripotency confirmed by immunofluorescent staining for pluripotency markers and...

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Identifiers

PMID: 28395802
DOI: 10.1016/j.scr.2016.12.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Reprogramming of a human induced pluripotent stem cell (iPSC) line from a Parkinson's disease patient with a R1628P variant in the LRRK2 gene.PMID 28395802Read ↗

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