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Generation of induced pluripotent stem cells (NIMHi001-A) from a Parkinson's disease patient of East Indian ethnicity carrying LRRK2 I1371V variant.

Stem cell research - 1 Apr 2020

Datta Indrani, Sowmithra, Jagtap Soham, Potdar Chandrakanta, Yadav Ravi, Pal Pramod

Abstract excerpt

Mutations in the Leucine Repeat Rich Kinase-2 (LRRK2) gene have been reported in familial Parkinson's disease (PD) cases. We have generated induced pluripotent stem cells (iPSCs) using Sendai-virus reprogramming-method from peripheral blood mononuclear cells of PD-patient of East-Indian ethnicity carrying the I1371V mutation in LRRK2 gene. PD diagnosis was performed using Unified Parkinson's Disease rating scale...

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Ethnicity
Induced Pluripotent Stem Cells
Leucine
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Leukocytes, Mononuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Parkinson Disease

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PMID: 32244201
DOI: 10.1016/j.scr.2020.101768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Generation of induced pluripotent stem cells (NIMHi001-A) from a Parkinson's disease patient of East Indian ethnicity carrying LRRK2 I1371V variant.PMID 32244201Read ↗

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