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Molecular characterization of hepatitis B virus X gene in HIV-positive South Africans.

Virus genes - 1 Apr 2018

Gededzha Maemu P, Sondlane Tsakani H, Malinga Lesibana A, Burnett Rosemary J, Lebelo Ramokone L, Blackard Jason T, Mphahlele M Jeffrey, Selabe Selokela G

Abstract excerpt

Hepatitis B virus (HBV) infection is a major public health problem worldwide and the major cause of hepatocellular carcinoma (HCC) in South Africa. The role of HBV in HCC is not well understood, although the HBV X gene has been implicated as a critical factor. Data on the HBV X gene in HIV-positive South Africans are limited; thus, we investigated X gene variability in 24 HIV-infected treatment-naïve patients at...

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PMID: 29411271
DOI: 10.1007/s11262-018-1536-5

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