Article
Genotyping comparison of Mycobacterium leprae isolates by VNTR analysis from nasal samples in a Brazilian endemic region.
Pathogens and global health - 1 Mar 2018
Lima Luana Nepomueceno Costa, Frota Cristiane Cunha, Suffys Phillip Noel, Fontes Amanda Nogueira Brum, Mota Rosa Maria Salani, Almeida Rosa Livia Freitas, Andrade Pontes Maria Araci de, Gonçalves Heitor de Sá, Kendall Carl, Kerr Ligia Regina Sansigolo
Abstract excerpt
This study analyzed the genetic diversity by MIRU-VNTR of Mycobacterium leprae isolates from nasal cavities and related to epidemiological and clinical data. The sample consisted of 48 newly diagnosed leprosy cases that tested positive for M. leprae PCR in nasal secretion (NS) attending to the National Reference Center of Dermatology Dona Libania (CDERM), Fortaleza, Brazil. Total DNA was extracted from NS of each...
Topics
- Adolescent
- Adult
- Aged
- Body Fluids
- Brazil
- Child
- Cluster Analysis
- Cross-Sectional Studies
- Female
- Genetic Variation
- Genotype
- Genotyping Techniques
- Humans