Article
Synergistical action of the β2 adrenoceptor and fatty acid binding protein 2 polymorphisms on the loss of glomerular filtration rate in Chinese patients with type 2 diabetic nephropathy.
International urology and nephrology - 1 Apr 2018
Wang Tao, Zhang Yan, Wang Ning, Liu Qiong, Wang ZeKai, Liu Bing, Niu Kai
Abstract excerpt
PURPOSE: Since altered sympathetic nerve activity and insulin resistance are implicated in the pathogenesis of type 2 diabetic nephropathy, we investigated the effect of polymorphic Arg16Gly and Gln27Glu in the β2 adrenoceptor gene and Ala54Thr in the fatty acid binding protein 2 gene on the estimated glomerular filtration rate (eGFR) in Chinese patients with the above disease. METHODS: A total of 552 diabetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.