Article
[Variation and Clinical Significance of LNK Gene in Essential Thrombocytosis].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2018
Tian Run-Mei, Rong Ying, Wu Liu-Song, Jiang Yan, Qing Hai-Yan, Zhu Ping, Chen Yan
Abstract excerpt
OBJECTIVE: To explore the mutation and single nucleotide polymorphism(SNP) of LNK gene in the patients with essential thrombocytosis (ET), and to analyze the relationship between LNK gene variation and the occurrence of ET. METHODS: JAK2V617F mutation was identified by allele-specific PCR. The whole exon of LNK gene was amplified by PCR. The amplified sequences included the Rs3184504 (C/T) and Rs78894077...
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