Article
[Detection of Novel Antigen MLAA-34 Gene Mutation in Acute Monocytic Leukemia and Its Correlation with Efficacy].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2018
Lei Bo, Zhang Wang-Gang, Chen Yin-Xia, He Ai-Li, Cao Xing-Mei, Zhao Wan-Hong, Wang Jian-Li, Liu Jie, Ma Xiao-Rong, Yang Yun, Zhang Peng-Yu, Luo Jing, Meng Xin
Abstract excerpt
OBJECTIVE: To investigate the correlation of all exone mutation in MLAA-34 gene with chemotherapeutic efficacy for leukemia. METHODS: The expression level of MLAA-34 gene in 40 patients with AML-M5 and 5 healthy volunteers as control was detected by RT-PCR and its effect on chemotherapeutic efficacy were analyzed by RT-PCR; the effect of MLAA-34 gene mutation on overall survival (OS) and progression-free survival...
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