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Article

High throughput gene sequencing reveals altered landscape in DNA damage responses and chromatin remodeling in sporadic pancreatic neuroendocrine tumors.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Apr 2018

Ji Shunrong, Yang Wenting, Liu Jiang, Zhao Jingjing, Chen Liang, Ni Quanxing, Long Jiang, Yu Xianjun

Abstract excerpt

PURPOSE: The main objectives of this retrospective study were to survey the genetic landscape of PNETs in a clinical cohort by using the high throughput gene sequencing method and to determine cellular signaling networks affected by the uncovered gene mutations. MATERIALS AND METHODS: We retrieved the demographics and tumor characteristics of 13 patients. Cellular DNA was extracted from fresh snap frozen tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29395620
DOI: 10.1016/j.pan.2018.01.006

Genes

MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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