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Article

Tissue-resident mesenchymal stromal cells: Implications for tissue-specific antifibrotic therapies

31 Jan 2018

Abstract excerpt

Recent scientific findings support the notion that fibrosis is driven by tissue-specific cellular and molecular mechanisms. Analysis of seemingly equivalent mesenchymal stromal cell (MSC) populations residing in different organs revealed unique properties and lineage capabilities that vary from one anatomical location to another. We review recently characterized tissue-resident MSC populations with a prominent...

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PMID: 29386358
DOI: 10.1126/scitranslmed.aan5174

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