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Article

MRI Indices of Cortical Development in Young People With Psychotic Experiences: Influence of Genetic Risk and Persistence of Symptoms.

Schizophrenia bulletin - 1 Jan 2019

Fonville Leon, Drakesmith Mark, Zammit Stanley, Lewis Glyn, Jones Derek K, David Anthony S

Abstract excerpt

Background: Psychotic experiences (PEs) are considered part of an extended psychosis phenotype and are associated with an elevated risk of developing a psychotic disorder. Risk of transition increases with persistence of PEs, and this is thought to be modulated by genetic and environmental factors. However, it is unclear if persistence is associated with progressive schizophrenia-like changes in neuroanatomy....

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Identifiers

PMID: 29385604
DOI: 10.1093/schbul/sbx195
PMCID: PMC6293214

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