Article
Brain structural trajectories in youth at familial risk for schizophrenia or bipolar disorder according to development of psychosis spectrum symptoms.
Journal of child psychology and psychiatry, and allied disciplines - 1 Jun 2021
Sugranyes Gisela, de la Serna Elena, Ilzarbe Daniel, Pariente Jose Carlos, Borras Roger, Romero Soledad, Rosa Mireia, Baeza Inmaculada, Moreno Maria Dolores, Bernardo Miguel, Vieta Eduard, Castro-Fornieles Josefina
Abstract excerpt
BACKGROUND: The evaluation of child and adolescent offspring of patients with schizophrenia (SzO) or bipolar disorder (BpO) may help understand changes taking place in the brain in individuals at heightened risk for disease during a key developmental period. METHODS: One hundred twenty-eight individuals (33 SzO and 46 BpO, considered jointly as 'Familial High Risk' (FHR), and 49 controls) aged 6-17 years...
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