Article
Identification and functional study of the endoplasmic reticulum stress sensor IRE1 in Chlamydomonas reinhardtii.
The Plant journal : for cell and molecular biology - 1 Apr 2018
Yamaoka Yasuyo, Choi Bae Young, Kim Hanul, Shin Seungjun, Kim Yeongho, Jang Sunghoon, Song Won-Yong, Cho Chung H, Yoon Hwan Su, Kohno Kenji, Lee Youngsook
Abstract excerpt
In many eukaryotes, endoplasmic reticulum (ER) stress activates the unfolded protein response (UPR) via the transmembrane endoribonuclease IRE1 to maintain ER homeostasis. The ER stress response in microalgae has not been studied in detail. Here, we identified Chlamydomonas reinhardtii IRE1 (CrIRE1) and characterized two independent knock-down alleles of this gene. CrIRE1 is similar to IRE1s identified in budding...
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