The miR-181 family promotes cell cycle by targeting CTDSPL, a phosphatase-like tumor suppressor in uveal melanoma

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) have been shown to function in many different cellular processes, including proliferation, apoptosis, differentiation and development. miR-181a, -181b, -181c and -181d are miR-181 members of the family, which has been rarely studied, especially uveal melanoma. METHODS: The expression level of miR-181 family in human uveal melanoma cell lines was measured via real-time PCR (RT-PCR)....

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