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Article

Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes

29 Jan 2018

Abstract excerpt

Virus reprogramming of cellular metabolism is recognised as a critical determinant for viral growth. While most viruses appear to activate central energy metabolism, different viruses have been shown to rely on alternative mechanisms of metabolic activation. Whether related viruses exploit conserved mechanisms and induce similar metabolic changes is currently unclear. In this work we investigate how two...

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PMID: 29377936
DOI: 10.1371/journal.ppat.1006835

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