Article
Possible effect of SNAIL family transcriptional repressor 1 polymorphisms in non-syndromic cleft lip with or without cleft palate.
Clinical oral investigations - 1 Sept 2018
Cura Francesca, Palmieri Annalisa, Girardi Ambra, Carinci Francesco, Morselli Paolo Giovanni, Nouri Nayereh, Pezzetti Furio, Scapoli Luca, Martinelli Marcella
Abstract excerpt
OBJECTIVE: Orofacial development is a complex process subjected to failure impairing. Indeed, the cleft of the lip and/or of the palate is among the most frequent inborn malformations. The JARID2 gene has been suggested to be involved in non-syndromic cleft lip with or without cleft palate (nsCL/P) etiology. JARID2 interacts with the polycomb repressive complex 2 (PRC2) in regulating the expression patterns of...
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