Article
Effect of dolutegravir in combination with Nucleoside Reverse Transcriptase Inhibitors (NRTIs) on people living with HIV who have pre-existing NRTI mutations.
International journal of antimicrobial agents - 1 May 2018
Sörstedt Erik, Carlander Christina, Flamholc Leo, Hejdeman Bo, Svedhem Veronica, Sönnerborg Anders, Gisslén Magnus, Yilmaz Aylin
Abstract excerpt
Until the introduction of dolutegravir (DTG), people living with HIV (PLWH) who have developed nucleoside reverse transcriptase inhibitor (NRTI) mutations have had few other treatment options outside of regimens based on ritonavir-boosted protease inhibitors (PI/r). Here we report treatment results among PLWH in Sweden with pre-existing NRTI mutations on antiretroviral treatment (ART) with DTG and one to two...
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