Article
Safety, Activity, and Biomarkers of SHR-1210, an Anti-PD-1 Antibody, for Patients with Advanced Esophageal Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2018
Huang Jing, Xu Binghe, Mo Hongnan, Zhang Weilong, Chen Xuelian, Wu Dawei, Qu Dong, Wang Xingyuan, Lan Bo, Yang Beibei, Wang Pei, Zhang Hongtu, Yang Qing, Jiao Yuchen
Abstract excerpt
Purpose: The current management of advanced esophageal squamous cell carcinoma (ESCC) remains unsatisfactory. We investigated the safety, efficacy, and biomarkers of SHR-1210, an anti-PD-1 antibody, in patients with recurrent or metastatic ESCC.Experimental Design: This study was part of a phase I trial in China. Patients with advanced ESCC who were refractory or intolerant to previous chemotherapy were enrolled....
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