Article
Misidentification of recombinant hepatitis C virus leading to treatment failure with direct acting antivirals.
Journal of medical virology - 1 May 2018
Mourez Thomas, Decroos Amandine, Goria Odile, Montialoux Hélène, De Oliveira Fabienne, Larrat Sylvie, Plantier Jean-Christophe, Riachi Ghassan
Abstract excerpt
The use of new Direct Acting Antivirals, specific of HCV, has greatly improved the HCV treatment. Most of the DAA are specific of HCV genotypes. Genotyping methods may target different regions of the HCV genome, though only the whole genome sequencing could confirm the correct genotype. The present study describes the virological investigation of a treatment failure due to the false identification of an unusual...
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