Article
Origin, prevalence and response to therapy of hepatitis C virus genotype 2k/1b chimeras.
Journal of hepatology - 1 Oct 2017
Susser Simone, Dietz Julia, Schlevogt Bernhard, Zuckerman Eli, Barak Mira, Piazzolla Valeria, Howe Anita, Hinrichsen Holger, Passmann Sandra, Daniel Rasha, Cornberg Markus, Mangia Alessandra, Zeuzem Stefan, Sarrazin Christoph
Abstract excerpt
BACKGROUND & AIMS: Little is known about the epidemiology and frequency of recombinant HCV genotype 2/1 strains, which may represent a challenge for direct antiviral therapy (DAA). This study aims to identify the epidemiology and phylogeny of HCV genotype 2/1 strains and encourages genotype screening, to select the DAA-regimen that achieves the optimal sustained virologic response. METHODS: Consecutive samples...
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