Article
Complex Segregation Analysis Provides Evidence for Autosomal Dominant Transmission in the Chinese Han Families with Ankylosing Spondylitis.
BioMed research international - 1 Jan 2017
Jiang Yutong, Lv Qing, Rao Shaoqi, Liao Zetao, Zhang Pingping, Yang Mingcan, Li Qiuxia, Cao Shuangyan, Lin Zhiming, Gu Jieruo
Abstract excerpt
INTRODUCTION: Familial aggregation of ankylosing spondylitis (AS) has been frequently noticed. However, the mode of inheritance in AS remains poorly understood. Our aim was to determine the mode of inheritance best fitting the observed transmission pattern of AS families. METHODS: Families with 5 or more AS patients diagnosed with 1984 modified New York criteria were recruited. We performed complex segregation...
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