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Article

Delayed Onset of Sleep in Adolescents With PAX6 Haploinsufficiency.

Biological research for nursing - 1 Mar 2018

Hanish Alyson E, Han Joan C

Abstract excerpt

OBJECTIVE: PAX6 haploinsufficiency ( +/-) can occur due to mutations involving only PAX6 in patients with isolated aniridia or as contiguous gene deletions in patients with Wilms tumor, aniridia, genitourinary anomalies, and range of developmental and intellectual disabilities syndrome. Given the role of PAX6 in pineal development and circadian regulation, adolescents with PAX6+/- may experience sleep-wake...

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Source

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Identifiers

PMID: 29343077
DOI: 10.1177/1099800417753670
PMCID: PMC5942528

Genes

PAX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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