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Exosomes originating from MSCs stimulated with TGF‐β and IFN‐γ promote Treg differentiation

16 Jan 2018

Abstract excerpt

Mesenchymal stem cells (MSCs) have been approved as a cellular drug for the treatment of a variety of immune-related diseases by the government of many countries'. Previous investigations, including ours, have shown that exosomes secreted by MSCs (MSC-ex) are one of the main factors responsible for the therapeutic effect of MSCs. However, the immune modulation activities and the contents of MSC-ex derived from...

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PMID: 29336475
DOI: 10.1002/jcp.26436

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