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Article

GATA4 Loss-of-Function Mutation and the Congenitally Bicuspid Aortic Valve.

The American journal of cardiology - 15 Feb 2018

Li Ruo-Gu, Xu Ying-Jia, Wang Juan, Liu Xing-Yuan, Yuan Fang, Huang Ri-Tai, Xue Song, Li Li, Liu Hua, Li Yan-Jie, Qu Xin-Kai, Shi Hong-Yu, Zhang Min, Qiu Xing-Biao, Yang Yi-Qing

Abstract excerpt

Aggregating evidence suggests that genetic determinants play a pivotal role in the pathogenesis of the congenitally bicuspid aortic valve (BAV). BAV is of pronounced genetic heterogeneity, and the genetic components underlying BAV in an overwhelming majority of patients remain elusive. In the current study, the whole coding exons and adjacent introns, as well as 5' and 3' untranslated regions of the GATA4 gene,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29325903
DOI: 10.1016/j.amjcard.2017.11.012

Genes

GATA4

Variants

Provenance

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