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Article

Strains of bacterial species induce a greatly varied acute adaptive immune response: The contribution of the accessory genome

11 Jan 2018

Abstract excerpt

A fundamental question in human susceptibility to bacterial infections is to what extent variability is a function of differences in the pathogen species or in individual humans. To focus on the pathogen species, we compared in the same individual the human adaptive T and B cell immune response to multiple strains of two major human pathogens, Staphylococcus aureus and Streptococcus pyogenes. We found wide...

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PMID: 29324905
DOI: 10.1371/journal.ppat.1006726

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