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Article

Behavioral fragmentation in the D1 CT ‐7 mouse model of Tourette's syndrome

3 Jan 2018

Abstract excerpt

AIM: The transgenic D1CT-7 mouse is one of the best-characterized animal models of Tourette's syndrome (TS), exhibiting spontaneous tic-like Head-Body Twitches (HBT) and deficits in sensorimotor gating. This study is aimed at evaluating the behavioral dynamics of these mutants and their potential relevance to TS. METHODS: The behavior of D1CT-7 and Wild Type littermates was firstly assessed by considering...

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PMID: 29314714
DOI: 10.1111/cns.12789

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