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Article

Physical constraints in cell fate specification. A case in point: Microgravity and phenotypes differentiation.

Progress in biophysics and molecular biology - 1 May 2018

Masiello Maria Grazia, Verna Roberto, Cucina Alessandra, Bizzarri Mariano

Abstract excerpt

Data obtained by studying mammalian cells in absence of gravity strongly support the notion that cell fate specification cannot be understood according to the current molecular model. A paradigmatic case in point is provided by studying cell populations growing in absence of gravity. When the physical constraint (gravity) is 'experimentally removed', cells spontaneously allocate into two morphologically different...

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PMID: 29307754
DOI: 10.1016/j.pbiomolbio.2018.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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