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Article

miR-132 serves as a diagnostic biomarker in gestational diabetes mellitus and its regulatory effect on trophoblast cell viability

25 Oct 2019

Abstract excerpt

BACKGROUND: Gestational diabetes mellitus (GDM) leads to poor pregnancy outcomes. Strategies that improve trophoblast cell function are important methods for GDM treatment. This study aimed to investigate the expression and diagnostic potential of microRNA-132 (miR-132) in GDM patients, and further analyzed the effects of miR-132 on HTR-8/SVneo cell proliferation. METHODS: Quantitative real-time PCR was applied...

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PMID: 31653266
DOI: 10.1186/s13000-019-0899-9

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