HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052.

doi:10.1097/QAI.0000000000001623

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052.

Journal of acquired immune deficiency syndromes (1999) - 15 Apr 2018

Palumbo Philip J, Fogel Jessica M, Hudelson Sarah E, Wilson Ethan A, Hart Stephen, Hovind Laura, Piwowar-Manning Estelle, Wallis Carole, Papathanasopoulos Maria A, Morgado Mariza G, Saravanan Shanmugam, Tripathy Srikanth, Eron Joseph J, Gallant Joel E, McCauley Marybeth, Gamble Theresa, Hosseinipour Mina C, Kumarasamy Nagalingeswaran, Hakim James G, Pilotto Jose H, Kumwenda Johnstone, Akelo Victor, Godbole Sheela V, Santos Breno R, Grinsztejn Beatriz, Panchia Ravindre, Chariyalertsak Suwat, Makhema Joseph, Badal-Faesen Sharlaa, Chen Ying Q, Cohen Myron S, Eshleman Susan H

Abstract excerpt

INTRODUCTION: We evaluated HIV drug resistance in adults who received early vs. delayed antiretroviral therapy (ART) in a multinational trial [HIV Prevention Trials Network (HPTN) 052, enrollment 2005-2010]. In HPTN 052, 1763 index participants were randomized to start ART at a CD4 cell count of 350-550 cells/mm (early ART arm) or <250 cells/mm (delayed ART arm). In May 2011, interim study results showed benefit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Secondary Prevention

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anti-Retroviral Agents

Share to Antiretroviral Therapy, Highly Active

Share to Clinical Trials as Topic

Share to Drug Resistance, Viral

Share to HIV

Share to Treatment Failure

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 29293156
DOI: 10.1097/QAI.0000000000001623
PMCID: PMC5844834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052.PMID 29293156Read ↗

Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase.Semantic proximity Read ↗

Baseline HIV-1 resistance, virological outcomes, and emergent resistance in the SECOND-LINE trial: an exploratory analysisSemantic proximity Read ↗

Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptaseSemantic proximity Read ↗

Transmitted drug resistance in ART-naive persons with acute/ early/ primary HIV infection: a systematic review and meta-analysisSemantic proximity Read ↗

Multiple drug class-wide resistance associated with poorer survival after treatment failure in a cohort of HIV-infected patients.Semantic proximity Read ↗

Brief Report: Comparative Analysis of Pre-existing HIV Drug Resistance Mutations in Proviral DNA Using Next-Generation Sequencing and Routine HIV RNA Genotyping.Semantic proximity Read ↗

Global HIV-1 transmitted drug resistance in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial.Semantic proximity Read ↗

Effect of immediate initiation of antiretroviral treatment on the risk of acquired HIV drug resistance.Semantic proximity Read ↗

Emergence of HIV drug resistance during first- and second-line antiretroviral therapy in resource-limited settings.Semantic proximity Read ↗

Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009.Semantic proximity Read ↗

Pretreatment HIV Drug Resistance and HIV-1 Subtype C Are Independently Associated With Virologic Failure: Results From the Multinational PEARLS (ACTG A5175) Clinical Trial.Semantic proximity Read ↗

Detection of HIV drug resistance during antiretroviral treatment and clinical progression in a large European cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.