Effect of immediate initiation of antiretroviral treatment on the risk of acquired HIV drug resistance.

doi:10.1097/QAD.0000000000001692

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Article

Effect of immediate initiation of antiretroviral treatment on the risk of acquired HIV drug resistance.

AIDS (London, England) - 28 Jan 2018

Lodi Sara, Günthard Huldrych F, Dunn David, Garcia Federico, Logan Roger, Jose Sophie, Bucher Heiner C, Scherrer Alexandra U, Schneider Marie-Paule, Egger Matthias, Glass Tracy R, Reiss Peter, van Sighem Ard, Boender T Sonia, Phillips Andrew N, Porter Kholoud, Hawkins David, Moreno Santiago, Monge Susana, Paraskevis Dimitrios, Simeon Metallidis, Vourli Georgia, Sabin Caroline, Hernán Miguel A

Abstract excerpt

OBJECTIVE: We estimated and compared the risk of clinically identified acquired drug resistance under immediate initiation [the currently recommended antiretroviral therapy (ART) initiation strategy], initiation with CD4 cell count less than 500 cells/μl and initiation with CD4 cell count less than 350 cells/μl. DESIGN: Cohort study based on routinely collected data from the HIV-CAUSAL collaboration. METHODS: For...

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PMID: 29135583
DOI: 10.1097/QAD.0000000000001692
PMCID: PMC5758415

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