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Article

Bladder dysfunction in Wolfram syndrome is highly prevalent and progresses to megacystis.

Journal of pediatric surgery - 1 Feb 2018

Wragg Ruth, Dias Renuka P, Barrett Timothy, McCarthy Liam

Abstract excerpt

AIM: Wolfram syndrome is a rare genetic defect in WFS1 or WSF2(CISD2). It includes diabetes mellitus and insipidis, sensorineural deafness, optic atrophy, but not bladder dysfunction. However, this has appeared a common finding in our national referral clinic, and we sought to quantify this problem. METHODS: Data were collected from a multidisciplinary team managing all Wolfram patients in the UK. The following...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29277467
DOI: 10.1016/j.jpedsurg.2017.11.025

Genes

CISD2
WFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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