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Article

Profiling microRNAs in individuals at risk of progression to rheumatoid arthritis

1 Dec 2017

Abstract excerpt

BACKGROUND: Individuals at risk of rheumatoid arthritis (RA) demonstrate systemic autoimmunity in the form of anti-citrullinated peptide antibodies (ACPA). MicroRNAs (miRNAs) are implicated in established RA. This study aimed to (1) compare miRNA expression between healthy individuals and those at risk of and those that develop RA, (2) evaluate the change in expression of miRNA from "at-risk" to early RA and (3)...

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PMID: 29273071
DOI: 10.1186/s13075-017-1492-9

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