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Article

The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis.

Scientific reports - 19 Dec 2017

Maggi Silvia, Balzani Edoardo, Lassi Glenda, Garcia-Garcia Celina, Plano Andrea, Espinoza Stefano, Mus Liudmila, Tinarelli Federico, Nolan Patrick M, Gainetdinov Raul R, Balci Fuat, Nieus Thierry, Tucci Valter

Abstract excerpt

Circadian clock is known to adapt to environmental changes and can significantly influence cognitive and physiological functions. In this work, we report specific behavioral, cognitive, and sleep homeostatic defects in the after hours (Afh) circadian mouse mutant, which is characterized by length...

Topics

Adaptation, Physiological
Animals
Behavior, Animal
Brain
Circadian Clocks
Circadian Rhythm
Female
Homeostasis
Male
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C3H

Mice, Inbred C57BL

Mutation

Sleep

Source

Open in PubMed Open full text

Identifiers

PMID: 29259298
DOI: 10.1038/s41598-017-18130-2
PMCID: PMC5736711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-29259298-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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