Article
The outer-membrane protein TolC of Vibrio cholerae serves as a second cell-surface receptor for the VP3 phage.
The Journal of biological chemistry - 16 Mar 2018
Fan Fenxia, Li Xu, Pang Bo, Zhang Cheng, Li Zhe, Zhang Lijuan, Li Jie, Zhang Jingyun, Yan Meiying, Liang Weili, Kan Biao
Abstract excerpt
Receptor recognition is a key step in the initiation of phage infection. Previously, we found that VP3, the T7 family phage of the Vibrio cholerae serogroup O1 biotype El Tor, can adsorb the core oligosaccharide (OS) of lipopolysaccharides of V. cholerae However, some wildtype strains of V. cholerae possessing the intact OS gene cluster still have VP3 binding but are resistant to VP3 infection. Moreover, an OS...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.