Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast Cancer

19 Dec 2017

Abstract excerpt

Abstract The angiotensin II receptor AGTR1, which mediates vasoconstrictive and inflammatory signaling in vascular disease, is overexpressed aberrantly in some breast cancers. In this study, we established the significance of an AGTR1-responsive NFκB signaling pathway in this breast cancer subset. We documented that AGTR1 overexpression occurred in the luminal A and B subtypes of breast cancer, was mutually...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Cytokine Signaling Pathways and Interactions
Share to Melanoma and MAPK Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29259013
DOI: 10.1158/0008-5472.can-17-1089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

The CARMA3–Bcl10–MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor–Positive Breast CancerPMID 29259013Read ↗

The Network of Angiotensin Receptors in Breast CancerSemantic proximity Read ↗

Breast Cancer Reveals Latent BMPR2-Related Susceptibility to Pulmonary Hypertension.Semantic proximity Read ↗

Elevated Plasma ACE2 and Shifted Ang 1-7/Ang II Ratios: A Novel Multi-Analyte Signature for Distinguishing Breast Cancer Patients from Healthy Controls—A Pilot Case-Control StudySemantic proximity Read ↗

Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.Semantic proximity Read ↗

Targeting AGTR1/NF-κB/CXCR4 axis by miR-155 attenuates oncogenesis in glioblastomaSemantic proximity Read ↗

ANGPTL4 overexpression is associated with progression and poor prognosis in breast cancerSemantic proximity Read ↗

Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer.Semantic proximity Read ↗

SARS-CoV-2 receptor ACE2 identifies immuno-hot tumors in breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.