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Article

Evaluation of plasma brain-derived neurotrophic factor levels and self-perceived cognitive impairment post-chemotherapy: a longitudinal study.

BMC cancer - 19 Dec 2017

Ng Terence, Lee Ying Yun, Chae Jung-Woo, Yeo Angie Hui Ling, Shwe Maung, Gan Yan Xiang, Ng Raymond C H, Chu Pat Pak Yan, Khor Chiea Chuen, Ho Han Kiat, Chan Alexandre

Abstract excerpt

BACKGROUND: Preliminary evidence suggests that changes in plasma brain-derived neurotrophic factor (BDNF) levels may contribute to the occurrence of chemotherapy-associated cognitive impairment (CACI), and a previous study suggested that carriers of the BDNF Met homozygous genotype are protected from CACI. METHODS: This multicenter, prospective cohort study involved chemotherapy-receiving early-stage breast...

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PMID: 29258453
DOI: 10.1186/s12885-017-3861-9
PMCID: PMC5735945

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BDNF

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